Mike's great-great great grandfather, Reuben Holloway, was born in Virginia around 1750, well before the Revolutionary War, and moved to South Carolina. The family story is that Reuben’s son, Levi, spent time in Florida with the Seminole Nation leader Osceola. Osceola’s mother was Mvskoke (Creek); they had fled Alabama for Florida, where displaced and local tribes combined to become the Seminole Nation. Forceful attempts to remove the Seminoles from Florida led to war. Osceola was treacherously seized during peace talks and imprisoned; Levi went to Fort Moultrie, near Charleston, to seek his release. Osceola died in prison several months later. Levi named one of his sons Osce and the name is still passed down in the family.
Mike’s great grandfather William Jordan Holloway was a teenage soldier in the Confederate Calvary and later attended the Medical College of Georgia in nearby Augusta. He was known as "Old Doctor” in family stories. He turned over his country medical practice to his son when “Dr. Willie”, Mike’s grandfather William Osce, completed medical training in Baltimore.
Mike’s father, “Dr. Jordan”, was a WWII Navy combat surgeon on Iwo Jima, with the Fifth Division of the Marine Corps, before returning home to South Carolina. Mike and his two brothers were the fourth generation of Holloways to become medical doctors.